Name: Prof. (Dr.) Suvrama Gupta                                                                                                   

Designation : Professor

 

        Dr. Gupta joined this Institute in February, 2008

 

Mobile No. : +919475116501

Phone No. : +913224 252900; Extn. 336
Email : suvg311@yahoo.co.in

 

Contact Details : 

Department of Biotechnology
Haldia Institute of Technology
ICARE Complex, HIT Campus, Haldia, PO-HIT                                                                                  
Dist. Purba Medinipur, West Bengal, INDIA
PIN-721657
 

 

Education

                 

Ph.D: (Bose Institute, Kolkata; awarded from Jadavpur University)                             Post Doctoral : Bose Institute, Kolkata                                                                                                          

Skills

Biochemistry, Protein Chemistry, Molecular Biology, Environment and ecology & Biophysical Chemistry

                         

Experience

Industrial Experience: 1994-1999 (East India Pharmaceutical Works Limited, Calcutta)

Teaching Experience: Teaching graduation and post graduation  students in the Department of Biotechnology, Haldia Institute of Technology, Haldia for the last 8 years

Course Taught

Odd Semester 2015-16

BT 302: Biochemistry Course Home
CHBT 301: Basic Environmental
Engineering & Elementary Biology
Course Home

MBT 101: Genetic Engineering

Course Home

BT 391: Biochemistry lab     Course Home

Even Semester 2015-16

BT-401: Molecular Biology

Course Home

BT-491: Molecular Biology     Course Home
 
Areas of Research

§ Structural biology, Cell Culture and Protein chemistry (Protein-drug interaction

§  Fermentation technology for bioactive molecule synthesis

Research Grants

1. Principal Investigator of the project entitled “Study of Tubulin-antimitotic compound interaction in search of novel active derivative targeting colchicine binding site on tubulin” 2012-2015 of (BT/Bio-CARE/01/184/2010-11; 34.9 lakh) funded by DBT (Department of Biotechnology, Govt. Of INDIA)  Status: Completed

2.  Selected as Visiting Fellow for the year 2010-11 in Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bangalore 

 

 
 
                                                            
Research Guidance at Doctoral level

B. Working as a Ph.D Scholars:  

1. Mr. Debanjan Jana; Registered at Maulana Abul Kalam Azad University of Technology, West Bengal.    

Publications

Updated View on Research Gate: https://www.researchgate.net/profile/Suvroma_Gupta

Books/Book Chapter:

 

Refereed Journal Publications:

  1. Suvroma Gupta, Shalmali Chakraborty, Asim Poddar, Nabaniota Sarkar, Kali P. Das, Bhabatarak Bhattacharyya. BisANS Binding to Tubulin: Isothermal Titration Calorimetry and the Site-specific Proteolysis Reveal the GTP-induced Structural Stability of Tubulin. PROTEINS: Structure, Function, and Genetics. 50:283-289 (2003)

 

  1. Suvroma Gupta, Bhabatarak Bhattacharyya. Antimitotic drugs binding to vinca domain of tubulin. Molecular and Cellular Biochemistry. 253: 41-47, (2003)

 

  1. Shalmali Chakraborty, Suvroma Gupta, Taradas Sarkar, Asim Poddar, Jose Pena, Rafael Solana, Raquel Tarazona, Bhabatarak Bhattacharyya. The B-Ring Substituent at C-7 of Colchicine and the α-C-Terminus of Tubulin Communicate Through the “Tail-Body” Interaction. PROTEINS: Structure, Function, and Bioinformatics. 57:602-9. (2004)

 

  1. Taradas Sarkar, Gopa Mitra, Suvroma Gupta, Tapas Manna, Asim Poddar, Dulal Panda, Kali P. Das, Bhabatarak Bhattacharyya. MAP2 prevents protein aggregation and facilitates reactivation of unfolded enzymes.Implications for the chaperone-like activity of MAP2. Eur. J. Biochem. 271, 1488-96 (2004).

 

  1. Lalita Das, Ajit B. Datta, Suvroma Gupta, Asim Poddar, Suparna Sengupta, Mark E. Janik, Bhabatarak Bhattacharyya. NH-Dansyl Isocolchicine exhibits a significantly improved tubulin binding affinity and microtubule inhibition in comparison to Isocolchicine by binding tubulin through it’s a and B ring. Biochemistry 44, 3249-58 (2005).

 

  1. Suvroma Gupta, Mithu Banerjee, Asim Poddar, Asok Banerjee, Gautam Basu, Debjani Roy, Bhabatarak Bhattacharyya. Biphasic Kinetics of the Colchicine-Tubulin Interaction: Role of Amino Acids   Surrounding the A ring of Bound Colchicine Molecule. Biochemistry 44: 10181-10188 (2005).

 

  1. Suvroma Gupta, Lalita Das, Asim Poddar, Mark E. Janik, Bhabatarak Bhattacharyya. Oxalone and lactone moieties of podophyllotoxin exhibit properties of both the B and C rings of colchicine in its binding with tubulin. Biochemistry 45:6467-6475. (2006).

 

  1. Bhabatarak Bhattacharyya, Dulal Panda, Suvroma Gupta, Mithu Banerjee. Anti mitotic Activity of Colchicine and its Structural basis for its interaction with Tubulin. Medicinal  research Reviews 2008 ;28(1):155-83. Review.

 

  1. Lalita Das, Suvroma Gupta, Asim Poddar, Mark E. Janik, Bhabatarak Bhattacharyya. Binding of indanocine to the colchicine site on tubulin promotes fluorescence, and its binding parameters resemble those of the colchicine analogue AC. Biochemistry. 48(7):1628-35. (2009)

 

10.  Chakraborti S, Chakravarty D, Gupta S, Chatterji BP, Dhar G, Poddar A, Panda D, Chakrabarti P, Ghosh Dastidar S, Bhattacharyya B. Discrimination of Ligands with Different Flexibilities Resulting from the Plasticity of the Binding Site in Tubulin. Biochemistry. Aug 27, (2012)