Name: Dr. Sudip Das                                                                                                       

Designation : Associate Professor

 

        Dr. Das joined this Institute in January, 2007

 

Mobile No. : +919433144054

Phone No. : +913224 252900; Extn.336
Email : sudipka@rediffmail.com

 

Contact Details : 

Department of Biotechnology
Haldia Institute of Technology
ICARE Complex, HIT Campus, Haldia, PO-HIT                                                                                  
Dist. PurbaMedinipur, West Bengal, INDIA
PIN-721657
 

 

Education

                 

Ph.D. (Kalyani University, Kalyani, Nadia)                                                                          Post Dctoral (Kalyani University, Kalyani, Nadia)     

Skills

Protein purification and analysis, Biochemical and Biophysical studies of proteins, Studies of biological and pathological role of proteinases/antiproteinases with biomedical importance

Experience

Teaching Experience: Since January, 2007 teaches B. Tech and M. Tech students in the Department of Biotechnology, Haldia Institute of Technology, Haldia.

Course Taught

Odd Semester 2015-16

MBT-115E: Biophysical Chemistry

Course Home

MBT-704C: Biomaterials

Course Home

·     CH(BT)-302: Chemistry II for BT

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CH(BT)-382: Chemistry -2 Lab for BT

Course Home

·     CHE:392: Instrumental Method of Analysis Lab

Course Home

Even Semester 2015-16

MBT-204: Downstream Processing

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BT-604A: Bioseparation Technology

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BT-694: Seminar (Review and Presentation by PPT)

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BT-891: Design Lab /Industrial problem/Industrial related training

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Areas of Research

§  Structural and functional analysis of MMPs and TIMPs and their role in human diseases.

§  Basic research in these themes is applied to understanding the role of signal transduction mechanisms under oxidant triggered condition in pathological condition and the role of proteinases/anti-proteinases therein.

 

 
 
                                                            
Publications

Updated View on ResearchGate: https://www.researchgate.net/profile/Sudip_Das10

Books/Book Chapter:

  1. T. Chakraborti, S. Das, M. Mandal, A. Mandal, S. Chakraborti: Ca2+ dynamics under oxidant stress in the cardiovascular system. In: Cell and Molecular Responses to Stress. Protein Adaptations and Signal Transduction. Vol.2. Chapter 16, Eds K.B. Storey and J. Storey. Elsevier Science, New York, 2001

Refereed Journal Publications:

  1. S. Das, S. Bandopadhyay and S. Das: Insights into the Role of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Health and Disease; Current Chemical Biology, Bentham Science, Volume 8; Number 3; Pp: 184 – 214, 2014

  2. S. Das and A. Maiti: Matrix Metalloproteinases in Subjects With Type 2 Diabetes Mellitus: Pattern of MMP-2 and MMP-9 Profile in Diabetes Mellitus Type-2 Patients. American International Journal of Research in Formal, Applied & Natural Sciences, 3(1), June-August, 2013, pp. 57-60, 2013

  3. A. Maiti, S. Das, N. Bhattacharyya: High gelatinase activity of a newly isolated polycyclic aromatic hydrocarbon degrading bacteria Bacillus weihenstephanensis strain AN1. JOURNAL OF PHARMACY RESEARCH, 6: 199-204, 2013

  4. A. Maiti, S. Das, N. Bhattacharyya: Isolation and Characterization of a New Bacterial strain from Petroleum Oil Contaminated Soil, India, Journal of Science (JOS), Vol. 2, No. 2, pp. 103-108

  5. A. Maiti, S. Das, N. Bhattacharyya: Bioremediation of High Molecular Weight Polycyclic Aromatic Hydrocarbons by Bacillus thuringiensis Strain NA2, Journal of Science (JOS), Vol. 1, No. 4, pp. 72-75, 2012

  6. S. Chakraborti, S. Das, P. Kar, B. Ghosh, K. Samanta,  S. Kolley, S. Ghosh, S. Roy, T. Chakraborti: Calcium signaling phenomena in heart diseases: a perspective. Molecular and Cellular Biochemistry 298 (Numbers 1-2): 1-40, 2007

  7.  A. Mandal, S. Das, T. Chakraborti, P. Kar, B. Ghosh, S. Chakraborti: Solubilization, purification and reconstitution of Ca2+-ATPase from bovine pulmonary artery smooth muscle microsomes by different detergents: Preservation of native structure and function of the enzyme by DHPC. Biochim. Biophys. Acta 1760: 20-31, 2006

  8. T. Chakraborti, S. Das, S. Chakraborti: Proteolytic Activation of Protein Kinase Ca by Peroxynitrite in Stimulating Cytosolic Phospholipase A2 in Pulmonary Endothelium: Involvement of a Pertussis Toxin Sensitive Protein. Biochemistry 44: 5246 – 5257, 2005

  9.  A. Mandal, T. Chakraborti, R. Choudhury, B. Ghosh, A.N. Ghosh. S. Das, S. Chakraborti: Role of MMP-2 in inhibiting Na+ dependent Ca2+ uptake by H2O2 in microsomes isolated from pulmonary smooth muscle. Molecular and Cellular Biochemistry 270: 79–87, 2005

  10.  S. Chakraborti, A. Mandal, S. Das, T. Chakraborti: Role of MMP-2 in PKCd-mediated inhibition of Na+ dependent Ca2+ uptake in microsomes of pulmonary smooth muscle: Involvement of a pertussis toxin sensitive protein. Molecular and Cellular Biochemistry 280: 107-117, 2005.

  11. S. Chakraborti, S. Das, T. Chakraborti: Oxidant-mediated activation of cytosolic phospholipase A2 in pulmonary endothelium: Role of protein kinase Ca and a pertussis toxin sensitive protein. Endothelium 12: 121-131, 2005

  12. S. Das, M. Mandal, A. Mandal, T. Chakraborti, S. Chakraborti: Identification, purification and characterization of matrix metalloproteinase-2 in bovine pulmonary artery smooth muscle plasma membrane. Molecular and Cellular Biochemistry 258: 73-89, 2004

  13. S. Das, A. Mandal, M. Mandal, T. Chakraborti, S. Chakraborti: Isolation of MMP-2 from MMP-2/TIMP-2 complex: characterization of the complex and the free enzyme in pulmonary vascular smooth muscle plasma membrane. Biochim. Biophys. Acta 1674: 158– 174, 2004

  14. S. Chakraborti, A. Mandal, S. Das, T. Chakraborti: Inhibition of Na+/Ca2+ exchanger by peroxynitrite in microsomes of pulmonary smooth muscle: Role of matrix metalloproteinase-2. Biochim. Biophys. Acta, 1671: 70-78, 2004

  15. A. Mandal, T. Chakraborti, S. Das, B. Ghosh, A. Ghosh, S. Chakraborti: Matrix metalloproteinase-2 mediated inhibition of Na+ dependent Ca2+ uptake by superoxide radical (O2.-) in microsomes of pulmonary smooth muscle. IUBMB Life 56:  267 – 276, 2004.

  16. S. Das, M. Mandal, T. Chakraborti, A. Mandal, S. Chakraborti: Structure and evolutionary aspects of matrix metalloproteinases: A brief overview. Molecular and Cellular Biochemistry 253: 31-40, 2003

  17. M. Mandal, S. Das, T. Chakraborti, A. Mandal, S. Chakraborti: Role of the matrix metalloproteinase-2 in the oxidant activation of Ca2+-ATPase by hydrogen peroxide in pulmonary vascular smooth muscle plasma membrane. Journal of Bioscience 28: 205-213, 2003

  18. M. Mandal, S. Das, T. Chakraborti, A. Mandal, S. Chakraborti: Identification, purification and partial characterization of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in bovine pulmonary artery smooth muscle. Molecular and Cellular Biochemistry 254: 145-155, 2003

  19. M. Mandal, A. Mandal, S. Das, T. Chakraborti, S. Chakraborti: Clinical implications of matrix metalloproteinases. Molecular and Cellular Biochemistry 252: 305-329, 2003

  20. S. Chakraborti, M. Mandal, S. Das, A. Mandal, T. Chakraborti: Regulation of matrix metalloproteinases: An overview. Molecular and Cellular Biochemistry 253: 269-285, 2003

  21. M. Mandal, A. Mandal, S. Das, T. Chakraborti, S. Chakraborti: Identification, purification and partial characterization of tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in bovine pulmonary artery smooth muscle. Molecular and Cellular Biochemistry 254: 275-287, 2003

  22. M. Mandal, T. Chakraborti, S. Das, A. Mandal, S. Chakraborti: Matrix metalloprotease 2-mediated activation of Ca2+-ATPase by superoxide radical (O2.-) in plasma membrane of bovine pulmonary vascular smooth muscle. Indian Journal Biochem. Biophys. 39: 390-396, 2002

  23. T. Chakraborti, S. Das, M. Mandal, A. Mandal, S. Chakraborti: Role of Ca2+-Dependent Metalloprotease-2 in stimulating Ca2+ATPase activity under peroxynitrite treatment in bovine pulmonary artery smooth muscle membrane. IUBMB Life 53: 167-173, 2002

  24. S. Das, T. Chakraborti, M. Mandal, A. Mandal, S. Chakraborti: Role of membrane-associated Ca2+ dependent matrix metalloprotease-2 in the oxidant activation of Ca2+-ATPase by tertiary butylhydroperoxide. Molecular and Cellular Biochemistry 237: 85-93, 2002

  25. S. Chakraborti, T. Chakraborti, M. Mandal, A. Mandal, S. Das, S.N. Ghosh: Protective role of magnesium in cardiovascular diseases: A review. Molecular and Cellular Biochemistry 238: 163-179, 2002

  26. T. Chakraborti, A. Mandal, M. Mandal, S. Das, S. Chakraborti: Complement activation in heart diseases: role of oxidants. Cellular Signalling 12: 607-617, 2000

  27. T. Chakraborti, S. Das, M. Mandal, S. Roychoudhury, S. Chakraborti: Oxidant, Mitochondria and Calcium: An Overview. Cellular Signalling 11: 77-85, 1999

  28. T. Chakraborti, M. Mandal, S. Das, S. Chakraborti: Age-dependent change in arachidonic acid metabolic capacity in rat alveolar macrophages. Biochem. Mol. Biol. Int. 47: 501-507, 1999

  29. S. Chakraborti, T. Chakraborti, M. Mandal, S. Das, S.K. Batabyal: Hypothalamic-pituitary-thyroid axis status of humans during development of ageing process. Clinica Chimica Acta 288: 137-145, 1999

  30. S. Chakraborti, T. Chakraborti, S. Das, M. Mandal, S.K. Batabyal: Acute phase proteins pattern in serum of healthy term and preterm infants at the early developmental stage to age six months. Medical Science Research 27: 335-336, 1999

  31. S. Chakraborti, S.K. Batabyal, M. Mandal, S. Das, T. Chakraborti: Protective action of vitamin C against hyperoxia-induced inhibition of microsomal Ca2+ uptake in pulmonary vascular smooth muscle of developing newborn rabbit. Medical Science Research 27: 83-85, 1999

Refereed Conference Publications:

  1.      Poster presentation in the National Symposium on “Molecular mechanism of Diseases and Drug Action (MMDDA)” held in the Saha Institute of Nuclear Physics, Calcutta, 16-18 Nov. 2005

  2.     Poster presentation in the “National Seminar on Recent Advances in Stress Physiology, Toxicology and Immunology” held in the University of Kalyani from 27-28 Nov. 2003.

  3.     Poster presentation in the “National Seminar on Recent Advancement in Molecular Physiology” held in the University of Kalyani from 4-6 Feb. 2002.

  4.      Participation in the National Workshop on “Multidisciplinary Approaches in Modern Biology, Education, Research and Employment” from the University of Kalyani held in University of Kalyani on 1-2 Feb. 2001.

  5.      Use of enzyme Biosensor: Monalisa Kayal, Sudip Das & Sebak R Roy; Haldia Institute of Technology, WestBengal, Presented at the National Conference on Emerging Technology & Technical Education ET & TE 2007 organized by Haldia Institute of Technology, W.B. on Feb 24 & 25, 2007

  6.      MEMBRANE SYSTEMS - WAY TO PYROGEN FREE WATER: Monalisa Kayal, Sudip Das & Sebak R Roy; Haldia Institute of Technology, W.B. Presented at the National Seminar on Membrane Separation and Its Application In Industry organized by Department of Chemical Engineering, Haldia Institute of Technology, West Bengal on 23rd March, 2007

  7.    USE OF PERVAPORATION IN EXTRACTION OF ETHANOL: Tiyasha Mondal, Sudip Das & Sebak R Roy; Haldia Institute of Technology, W.B. Presented at the National Seminar on Membrane Separation and Its Application In Industry organized by Department of Chemical Engineering, Haldia Institute of Technology, West Bengal on 23rd March, 2007

  8.      BIOCHIPS-THE BIOLOGICAL COMPUTER: Monalisa Kayal, Sudip Das & Sebak R Roy; Haldia Institute of Technology, WB. Presented at the National Seminar on “BIOTECHNOLOGY: PRESENT SCENARIO AND FUTURE LANDMARKS” on 29 March 2007 organized by Department of Biotechnology, Haldia Institute of Technology, West Bengal.

  9.       Maiti, A., A. Mukhopadhyay, K. Halder, and S. Das. 2013. Bioremediation of Polycyclic Aromatic Hydrocarbons by Bacillus thuringiensis Strain NA2 Isolated from Haldia Refinery Site, West Bengal at the 100th Science Congress, Kolkata, India.

  10.    Natural Source for the Treatment of Diseases : Role of Matrix Metalloproteinases and their Inhibitors in the symposium “Environmental Impact on Biodiversity and Plant Development” 19th-20th February, 2015, Presidency University.

  11.     Poster presentation by S. Das, S. Bandopadhyay and S. Das (2013) in Proceedings of National Seminar on New Horizone in Biotechnology, West Bengal, India. pp. 95-98.

  12.      Poster presentation by S. Das, R. Kundu and R. Naga (2013) Proceedings of National Seminar on New Horizone in Biotechnology, West Bengal, India. pp. 99-104.